While most liver damage and liver disease is caused by cirrhosis and hepatitis, many pharmaceutical drugs are now the cause of liver damage. Ketek, an antibiotic used for bacterial infections are one of the drugs that cause liver damage, liver failure, and death. Symptoms of liver disease include nausea and vomiting, loss of appetite, weight loss, jaundice, extreme itching sensation, vomiting blood, dark urine, shortness of breath, lack of blood clotting, and mental confusion. When liver failure occurs, a liver transplant is necessary. (Ketek)